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Customer reviews for Prilosec OTC Heartburn & Acid Reducer Tablets, 20 mg, 42 ct. for
Prilosec OTC Heartburn & Acid Reducer Tablets, 20 mg, 42 ct.
4.8 out of 5 stars
stars
1,353 ratings237 reviews
  1. 5 stars91% (1,228)
  2. 4 stars6% (79)
  3. 3 stars2% (26)
  4. 2 stars0% (4)
  5. 1 star1% (16)
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Showing 171-180 of 237 reviews
Jul 25, 2025
Reviewer name: Sheldon
5 out of 5 stars
5 out of 5 stars review

Verified Purchase

Putting in a new toilet

It looks like a great toilet haven't put it in.

Helpful?155JS8E8WCCM3700027004
Jul 12, 2023
Reviewer name: misti911
5 out of 5 stars
5 out of 5 stars review

No more heartburn

[This review was collected as part of a promotion.] I don't have to worry about heartburn anymore since taking Prilosec OTC. It works for 24 hours and stops heartburn before it starts. Also, It blocks acid for 24 hours. I can eat without having to worry about not feeling well afterwards.

Review from a P&G website
Helpful?155JS8E8WCCM3700027004
Jul 12, 2023
Reviewer name: Elizabeth S.
5 out of 5 stars
5 out of 5 stars review

Fast and effective!

[This review was collected as part of a promotion.] Prilosec OTC blocked my frequent heartburn! I used Prilosec OTC when my chicken curry caught up with me. I started using this product when I had heartburn in the afternoon for 3 days in a row. The tablets are easy to swallow, and I had relief after the second dose!

Review from a P&G website
Helpful?155JS8E8WCCM3700027004
Jul 14, 2023
Reviewer name: Sabrina P
5 out of 5 stars
5 out of 5 stars review

I switched from another heartburn product to Prilosec and noticed a positive difference.

[This review was collected as part of a promotion.] I switched from another heartburn product to Prilosec and noticed a positive difference. Between settling my heartburn and the pretty package, I am super happy with the results and found my new go-to. Loving how it is trusted by doctors for over 15 years and backed by science so I feel safe using it.

Review from a P&G website
Helpful?155JS8E8WCCM3700027004
Oct 27, 2014
Reviewer name: Billy1234
5 out of 5 stars
5 out of 5 stars review

Great product....Terrible packaging

I can't understand why a company would put such a small product in such a large package. A big colorful box full of three smaller colorful boxes in which each contains a blister pack of 14 pills. My simple minded suggestion is to put them all in a small plastic bottle which would be much easier on my arthritic hands to open.

Review from a P&G website
Helpful?155JS8E8WCCM3700027004
Jul 12, 2023
Reviewer name: Kellyr
5 out of 5 stars
5 out of 5 stars review

Heart Burn Relief I needed

[This review was collected as part of a promotion.] I highly recommend utilizing Prilosec OTC for relieving heartburn. Dealing with heartburn on a daily basis, especially during the night, can be dreadful. However, since I completed the 14-day course of Prilosec OTC, I have experienced a significant improvement. I no longer suffer from heartburn issues and no longer wake up in the middle of the night in pain, as I used to when relying solely on Tums for relief. Prilosec OTC has proven to be a game-changer in managing my heartburn effectively.

Review from a P&G website
Helpful?155JS8E8WCCM3700027004
Oct 2, 2012
Reviewer name: EastmeetsWest
5 out of 5 stars
5 out of 5 stars review

The Best

I have been using Prilosec for years. However, one side effect that is not listed is it depletes Vitamin B12 levels in the body. I had to being B12 injection therapy and tried other medications for heart burn. NOTHING else worked. However, I now get it as a prescriptions since my insurance does cover it. It is only $10.00 for a 3 month supply. I wish the OTC was cheaper. I do keep the OTC on hand for emergencies (I forget to get a refill). This is still the only product that works on my GERDS and my doctor wants me on as it protects my stomach from NSAID ulcers.

Review from a P&G website
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Jul 13, 2023
Reviewer name: lkw1974
5 out of 5 stars
5 out of 5 stars review

Works Great

[This review was collected as part of a promotion.] Prilosec is my absolute favorite heartburn medicine OTC. It works so well at stopping heartburn. It also works well at blocking it. I love how easy the pill is to swallow and it comes in a nice purple box so its easy to find. Prilosec gives me the confidence I need because it is trusted by doctors and backed by Science. It is a brand I know and trust especially since it works so well at slowing down the acid produced in the stomach. I defintiely recommend trying it

Review from a P&G website
Helpful?155JS8E8WCCM3700027004
Jun 26, 2011
Reviewer name: annie
5 out of 5 stars
5 out of 5 stars review

need new packaging

My parents & I all take Prilosec daily and have for years. It is totally effective & we love it. However the packaging is a miserable experience for us: I am disabled ( my dominate right hand), my Mother has severe arthritis & my Father's hand cramp painfully. It is a truly frustrating event wrestling with the package using scissors and things to poke holes. Please design & implement easier packaging. Thanks Annie

Review from a P&G website
Helpful?155JS8E8WCCM3700027004
Jul 12, 2023
Reviewer name: Lana_b
5 out of 5 stars
5 out of 5 stars review

Prilosec OTC Relieves Frequent Heartburn

[This review was collected as part of a promotion.] As I'm getting older, I'm discovering I have issues with certain foods. I may love pizza and spicy foods, but sometimes they don't like me later that night and waking up with heartburn interrupts my rest. Dealing with heartburn is no fun, but I've found using Prilosec OTC definitely helps. The pills are easy to swallow and there's nothing chalky to chew. While it is not instantaneous relief, it definitely helps relieve my symptoms and taking one a day helps keeps my symptoms at bay. It can take a few days to start working completely and you shouldn't take for more than a few weeks at a time without a break, but if you're battling frequent bouts of heartburn, Prilosec OTC is the over the counter medication to try. It's definitely helped my frequent heartburn.

Review from a P&G website
Helpful?155JS8E8WCCM3700027004