I am left-handed and the M650 fits my hand really well - especially the back buttons on the right side of the mouse. My hand no longer hurts when I use this mouse for protracted periods of time - which is every day. Also, this mouse is very quiet, but with good hand and finger-feel when clicking the buttons. Overall, very well done. I have been looking for a mouse like this for years and now I have found it!

The cat who often sleeps on a pillow on my laps is offended by the sound of mouse clicks. Over the years, I have tried three models of silent-clicky mouses, with the M650 being my favorite. I like it because it has soft-ish rubber sides, a rubber-coated scroll wheel that spins silently, and most of all, near-silent finger-button clicks. At first, the smaller size of the mouse seemed weird, but now that I am used to it, the bigger mice seem too big, and I have medium-sized hands for a man. I am glad it does not have an RGB light show, which I find distracting. The thumb buttons on the left-side are useful to have but placed too far back for my thumb to reach them comfortably. If Logitech were to put the silent features into some of their more ergonomic (and expensive) mice, then I would definitely spend my money to upgrade, especially if it was one of their mice with the side-scrolling wheel that is useful for editing video and looking at spreadsheets. As for now, this mouse checks the most important boxes, and I am glad to have this option for a silent mouse.

[This review was collected as part of a promotion.] Love the large M650 for its silent clicks and how easily it fits in my hand. With smaller mice I need to curl my hand up, but this lets me keep it relaxed. I also love the MX Keys S and find it very satisfying to type on. Note that it has almost the full standard layout, but no official Print Screen key, only a screenshot key that opens the Windows snipping tool. Also, the function keys are slightly shifted over from their most traditional layout. But this is by far the best standard layout keyboard I’ve found. The buttons to switch the keyboard between computers work flawlessly. The mouse doesn’t switch, but I ended up buying a second one because I like it so much, and I just switch mice when I switch computers.

[This review was collected as part of a promotion.] I had a razer pro click mini before this mouse and want to say logi offers better quality for less money. Buttons and wheal are truly silent, and mouse feels great in hand. Pleasant materials. I am more than satisfied with the purchase.

[This review was collected as part of a promotion.] It is a great product to work woth.Silent as mentioned in the description and has various functionalities where we can customize the buttons through the logitech application which in terms of innovation is great. Color and texture of the mice is great and has a modern design touch to the mice.

[This review was collected as part of a promotion.] I bought an M650 mouse which worked perfectly with my computer. But it lacked the ability to work with (run away from) my cat, Shadow. He destroyed it. I have replaced the M650 mouse with a new one. The new one is kept safely in my hand or a drawer and he plays with the destroyed one.

Perfect bluetooth mouse. large, comfortable. Has a cool intuitive wheel for when you need to scroll quickly down a page. It's also light and easy to move around. Fits the hand comfortably. Very reliable features. Can turn it off and on to conserve battery. Great buy.

Noticeably more precise than our old low-end mouse. Feels & looks good. Recycled content is another plus. Wish the packaging had been all cardboard for easy recycling. Also would be nice if Logitech backed their higher end accessories with a two year warranty.

The M650 L feels different from all other Logitech mice I've used. It seems extra tall and narrow, so I have to grab it on the sides with more strength using my fingers, which is very uncomfortable. I would switch back to the cheaper M330 Silent Plus rather than using this.

Mouse feel smooth and light, I have the L size and fit comfortable in my hand, my only issue it's with the Bluetooth connection because sometimes the pointer takes few seconds to came back and delay after you are not using.... The USB connection it's the opposite, super fast with no delay or lags