I have used Equate drops with olopatadine with no problem. I have used ketotifen and never had a problem. Both worked very well. I got the 3 pack of Pataday. The first time I used it in one eye, my eye got itchy and it felt like someone was pressing on my eyeball. I used it again with the same problem. I didn't want to give up so the third time I used it was the worst. I spent the rest of the day with cold compresses on my eye. Having used drops with the same drug it has to be the brand. Either the strength or an additive caused the problem or it was contaminated.

They work great BUT the bottle was empty after using 12 drops. Ridiculous.