tylenol pm extra strength pain relief caplets 225 ct. Front-facing retail box with TYLENOL PM logo on red background, labeled Extra Strength and 225 caplets; inset shows two teal-green caplets marked Actual Size and text stating acetaminophen 500 mg and diphenhydramine HCl 25 mg per caplet, nighttime pain reliever and sleep aid.
Tylenol PM Extra Strength Pain Relief Caplets 225 ct.
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TYLENOL

Tylenol PM Extra Strength Pain Relief Caplets 225 ct.

|1,828 ratings

Highlights

Product is FSA & HSA eligible.

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  • One 225 count bottle of Tylenol PM Extra Strength Caplets
  • Pain reliever & nighttime sleep aid caplets
  • 500 mg. of acetaminophen and 25 mg of diphenhydramine HCl per caplet

Specifications

  • Use Instructions: Adults and children 12 years and over: Take 2 caplets at bedtime Do not take more than 2 caplets of this product in 24 hours. Children under 12 years: do not use
  • Pack Size and Unit of Measure: 225 Count, 500 mg of acetaminophen and 25 mg of diphenhydramine HCl per caplet
  • Shelf Life: N/A
  • FSA/HSA Eligible?: Yes
  • Allergen + Warnings information: Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: More than 4,000 mg of acetaminophen in 24 hours, with other drugs containing acetaminophen, 3 or more alcoholic drinks every day while using this product. Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include: Skin reddening, Blisters, Rash. If a skin reaction occurs, stop use and seek medical help right away.
  • Full Ingredient list: Active ingredients (in each caplet)
    Acetaminophen 500 mg
    Diphenhydramine HCl 25 mg
    Inactive ingredients: carnauba wax, crospovidone, FD&C blue no. 1 aluminum lake, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, povidone, pregelatinized starch, sodium starch glycolate, stearic acid, titanium dioxide
Current price is $20.989.3 ¢/ea
Prices may vary in club and online
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Shipping

Free for Plus on eligible orders over $50
Columbus, 43215
Arrives by Sat, Oct 31
Return or replace anytime.
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About this item

Product details

Tylenol PM Extra Strength Nighttime Pain Reliever and Sleep Aid Caplets are specifically designed to provide relief from minor aches and pains while helping you fall asleep quickly for a more restful night. Each caplet contains 500 mg of acetaminophen, which effectively alleviates discomfort, along with 25 mg of diphenhydramine hydrochloride, a non-habit-forming sleep aid that promotes quicker and uninterrupted sleep.  

This dual-action formula not only addresses pain but also helps you relax and drift off to sleep, making it an ideal choice for those struggling with headaches, minor aches, and sleeplessness. As the #1 doctor-recommended brand for pain relief and fever reduction, Tylenol PM is trusted by healthcare professionals and can be safely used by adults and children aged 12 years and older when used as directed.  

The caplets are formulated to help you fall asleep fast and stay asleep throughout the night, ensuring you wake up refreshed and ready to face the day. Tylenol PM Extra Strength Caplets are a reliable nighttime solution, providing the pain relief and rest you need to be your best self during the day. Keep Tylenol PM on hand for those nights when discomfort keeps you awake, and enjoy a better night’s sleep.

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Key specifications

Specifications

  • Use Instructions: Adults and children 12 years and over: Take 2 caplets at bedtime Do not take more than 2 caplets of this product in 24 hours. Children under 12 years: do not use
  • Pack Size and Unit of Measure: 225 Count, 500 mg of acetaminophen and 25 mg of diphenhydramine HCl per caplet
  • Shelf Life: N/A
  • FSA/HSA Eligible?: Yes
  • Allergen + Warnings information: Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: More than 4,000 mg of acetaminophen in 24 hours, with other drugs containing acetaminophen, 3 or more alcoholic drinks every day while using this product. Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include: Skin reddening, Blisters, Rash. If a skin reaction occurs, stop use and seek medical help right away.
  • Full Ingredient list: Active ingredients (in each caplet)
    Acetaminophen 500 mg
    Diphenhydramine HCl 25 mg
    Inactive ingredients: carnauba wax, crospovidone, FD&C blue no. 1 aluminum lake, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, povidone, pregelatinized starch, sodium starch glycolate, stearic acid, titanium dioxide

Indications

Health Concern

Arthritis Fever Headache

Member ratings & reviews

4.8 out of 5 stars
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1,828 ratings1,335 reviews
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  1. 5 stars85% (1,545)
  2. 4 stars10% (191)
  3. 3 stars3% (56)
  4. 2 stars1% (13)
  5. 1 star1% (23)
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Showing 1-3 of 1,335 reviews

Sep 29, 2026
Reviewer name: Bonnie
5 out of 5 stars
5 out of 5 stars review

Verified Purchase

Tylenol PM is the brand of nighttime sleep aid I have used for more than a decade. I trust it to help with nighttime stress and pain. It's my go-to where others have failed.

Review from walmart.com
Helpful?1SYOFUORYJY230045048236
Mar 10, 2026
Reviewer name: Kim
5 out of 5 stars
5 out of 5 stars review

Verified Purchase

I'm often dealing with insomnia and I find Tylenol PM is an easy and effective way to take care of tbe problems and get a nights rest. i wake up easilily and have no side effect it for anyone recommend it to anyone who has been having difficulty sleeping and Walmart pricing is also a plus.

Review from walmart.com
Helpful?1SYOFUORYJY230045048236
Aug 15, 2026
Reviewer name: Claudia
5 out of 5 stars
5 out of 5 stars review

Verified Purchase

I use this Tylenol PM before bedtime. When I take the Tylenol PM right before bedtime it relaxes me. Also I like it because I hardly use any Tylenol during the day.

Review from walmart.com
Helpful?1SYOFUORYJY230045048236
Current price is $20.989.3 ¢/ea
Prices may vary in club and online
How do you want your item?

Shipping

Free for Plus on eligible orders over $50
Columbus, 43215
Arrives by Sat, Oct 31
Return or replace anytime.

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