Mucinex 12 Hour Cold and Flu Medicine for Adults, 50 Tablets

Item # 990549445
Current price is $29.98
$0.60/ea
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Highlights

  •  The first and only over-the-counter cold and flu medicine that provides 12 hours of powerful multi-symptom relief
  • All Day Relief of Headache, Body Aches, Fever, Cough, & Chest Congestion

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4.8 out of 5 Stars. 1033 reviews
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Mucinex 12 Hour Cold and Flu Medicine for Adults, 50 Tablets
Mucinex 12 Hour Cold and Flu Medicine for Adults, 50 Tablets
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About this item

Product details

NEW MUCINEX 12 HOUR COLD & FEVER MULTI-SYMPTOM TABLETS

 Introducing the first and only over-the-counter 12 hour cold and flu medicine for adults that reduces fever and relieves cough, chest congestion, and body pain

ALL DAY OR NIGHT MULTI-SYMPTOM RELIEF

One dose lasts 3x longer than most cold & flu medicines (compared to 1 dose of 4-hour medicine without re-dosing)
FEVER REDUCTION & HEADACHE RELIEF: Contains Naproxen Sodium which reduces fever and relieves headache & minor pains

COUGH SUPPRESSANT

Contains Dextromethorphan HBr which helps control cough

info:
If the item details above aren't accurate or complete, we want to know about it. 

Specifications

HSA/FSA Eligible: Yes

Shelf Life: 24 Months

Allergy Alert: Naproxen sodium may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may include:  

hives  

facial swelling  

asthma (wheezing)  

shock  

skin reddening  

rash  

blisters  

If an allergic reaction occurs, stop use and seek medical help right away.  

Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you:  

are age 60 or older  

have had stomach ulcers or bleeding problems  

take a blood thinning (anticoagulant) or steroid drug  

take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others)  

have 3 or more alcoholic drinks every day while using this product  

take more or for a longer time than directed  

Heart attack and stroke warning: NSAIDs, except aspirin, increase the risk of heart attack, heart failure, and stroke. These can be fatal. The risk is higher if you use more than directed or for longer than directed.  

Do not use  

if you have ever had an allergic reaction to any other pain reliever/fever reducer  

for children under 12 years of age  

right before or after heart surgery  

if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.  

Ask a doctor before use if  

the stomach bleeding warning applies to you  

you have a history of stomach problems, such as heartburn  

you have high blood pressure, heart disease, liver cirrhosis, kidney disease, asthma, or had a stroke  

you are taking a diuretic  

you have problems or serious side effects from taking pain relievers or fever reducers  

you have persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema  

you have a cough accompanied by too much phlegm (mucus)  

Ask a doctor or pharmacist before use if you are  

under a doctor’s care for any serious condition  

taking aspirin for heart attack or stroke, because naproxen may decrease this benefit of aspirin  

taking any other drug  

When using this product  

take with food or milk if stomach upset occurs  

Stop use and ask a doctor if you experience any of the following signs of stomach bleeding:  

feel faint  

vomit blood  

have bloody or black stools  

have stomach pain that does not get better  

you have symptoms of heart problems or stroke:  

chest pain  

trouble breathing  

weakness in one part or side of body  

slurred speech  

leg swelling  

pain gets worse or lasts more than 10 days  

fever gets worse or lasts more than 3 days  

you have difficulty swallowing  

it feels like the pill is stuck in your throat  

redness or swelling is present in the painful area  

any new symptoms appear  

cough lasts more than 7 days, comes back, or occurs with fever, rash, or persistent headache. These could be signs of a serious illness.  

If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use naproxen sodium at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.  

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

Member ratings & reviews

4.8 out of 5 stars
stars
405 ratings405 reviews
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Showing 1-3 of 405 reviews

Jul 6, 2026
CristelG
5 out of 5 stars review

Last up to 12 hours so you dont have to take medicine throughout the day

[This review was collected as part of a promotion.] I started taking Mucinex 12HR Cold & Fever Multi-Symptom as soon as my cold symptoms started, and it made a huge difference. It helped relieve my cough, loosen the mucus, and reduced my body aches and headache. I also love that it lasts up to 12 hours, so I didn't have to keep taking medicine throughout the day. Definitely a great product to keep on hand during cold and flu season! Highly recommend. 💙

Review from influenster.com
Helpful?1RQMQLXT1NBQ6004981466
Jun 23, 2026
ErinH
5 out of 5 stars review

A top-tier cold and fever relief option I would choose again and again, hands down!

[This review was collected as part of a promotion.] I got sick this summer, and this helped me manage my symptoms so I could get back on my feet and handle what I needed to do for work. The tablets were easy to take and swallow, and I appreciated the convenience of 12-hour relief during a busy day. I also like having a multi-symptom option on hand rather than needing to reach for several different products the ingredients were designed to address multiple cold symptoms, and that was so convenient. Based on my experience, I would recommend it for keeping in your medicine cabinet when cold and fever symptoms come up. I did receive this Mucinex 12-hour cold and fever multi-symptom complimentary in exchange for my honest review. I would choose this again and again because it truly works.

Review from influenster.com
Helpful?1RQMQLXT1NBQ6004981466
Jul 15, 2026
tessieA
5 out of 5 stars review

Best cold,fever relief

[This review was collected as part of a promotion.] This works great when you have a cold and congested. Loved how it last for 12 hours and works. This will not disappoint if you are all congested,fever,cold. Helped me not be so congested and miserable. The pills are a little big and had to take one at a time, but goes down nicely.

Review from Mucinex
Helpful?1RQMQLXT1NBQ6004981466