Vicks PainQuil

Vicks PainQuil Pain Relief Liquid, Acetaminophen, 1000mg, 12 fl. oz., 3pk.

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Highlights

  • Three pack of 1 Daytime & 2 Nighttime 12 fl. oz. bottles
  • Maximum strength pain relief anytime + sleep aid at nighttime
  • Reliefs headache, backache, muscular ache, & other minor aches & pains
  • Non-habit-forming ingredient, helps you get the sleep you want
  • PainQuil (in each 30mL): Acetaminophen
  • PainQuil PM (in each 30mL): Acetaminophen, Diphenhydramine HCI
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4.6 out of 5 stars
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Vicks PainQuil Pain Relief Liquid, Acetaminophen, 1000mg, 12 fl. oz., 3pk.
Vicks PainQuil Pain Relief Liquid, Acetaminophen, 1000mg, 12 fl. oz., 3pk.
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About this item

Product details

Power through your pain with Vicks PainQuil and PainQuil PM adult liquid pain relievers.  

Day and Night Combo Pack:

For pain relief anytime, PainQuil Liquid Pain Reliever starts working fast for max strength‡ headache relief, backache relief, muscular ache relief, and other minor aches & pains. For pain relief at night, PainQuil PM Liquid Pain Reliever starts working fast for headache relief, backache relief, muscular ache relief, and other minor aches & pains + 50mg diphenhydramine HCl per dose to help you sleep soundly. PainQuil and PainQuil PM deliver max strength‡ pain relief with 1000mg Acetaminophen per dose.   

Delicious Cherry Flavor:

These adult pain reliever liquids are easy to take & deliciously flavored; PainQuil is black cherry flavored, and PainQuil PM is midnight cherry flavored.  

Non-Habit Forming:

Both PainQuil and PainQuil PM are non-habit forming. They are also free of high fructose corn syrup and free of sugar.  

PainQuil and PainQuil PM Liquid Pain Relievers are from the makers of Vicks, with over 125 years of health care expertise.   

‡Maximum strength dose of active ingredients per dosing interval, only use as directed.

info:
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Specifications

  • Use Instructions: PainQuil: Take only as directed. Do not exceed 3 doses (30 mL) per day (24 hours). Only use the dose cup provided.
    Adults & children 12 yrs & over: 30 mL every 6 hrs.
    Children under 12 yrs: ask a doctor
    PainQuil PM: Only use as directed. Take only one dose (30 mL) per day (24 hours). Only use the dose cup provided.
    Adults & children 12 yrs & over: 30 mL at bedtime
    Children under 12 yrs: do not use
  • Pack Size and Unit of Measure: Includes three (3) 12 fl. oz. bottles; Total 36 fluid ounces
  • Shelf Life: N/A
  • FSA/HSA Eligible?: Yes
  • Allergen + Warnings information: Allergen: Acetaminophen: 1000 mg (in each 30 mL)

    PainQuil
    Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take more than 3 doses (30 mL each) in 24 hours, which is the maximum daily amount for this product, with other drugs containing acetaminophen, 3 or more alcoholic drinks every day while using this product.
    Allergy Alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening, blisters, rash. If a skin reaction occurs, stop use and seek medical help right away.
    Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.

    Ask a doctor before use if you have: liver disease and/or a sodium-restricted diet.

    Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

    PainQuil PM
    Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take more than 3 doses (30 mL each) in 24 hours, which is the maximum daily amount for this product, with other drugs containing acetaminophen, 3 or more alcoholic drinks every day while using this product.
    Allergy Alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening, blisters, rash. If a skin reaction occurs, stop use and seek medical help right away.
    Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.

    Ask a doctor before use if you have: liver disease, a breathing problem such as emphysema or chronic bronchitis, glaucoma, difficulty in urination due to enlargement of the prostate gland, a sodium-restricted diet. When using this product avoid alcoholic beverages, drowsiness will occur, do not drive a motor vehicle or operate machinery.

    Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
  • Full Ingredient list
    • PainQuil:
      Active Ingredients: Acetaminophen 100mg
      Inactive ingredients: alcohol, anhydrous citric acid, FD&C Red No. 40, flavor, polysorbate 20, propylene glycol, saccharin sodium, sodium benzoate, sodium chloride, sodium citrate, sorbitol, sucralose, water, xanthan gum
    • PainQuil PM:
      Active Ingredients: Acetaminophen 100mg, Diphenhydramine HCI 50mg
      Inactive ingredients: alcohol, anhydrous citric acid, FD&C Blue No. 1, FD&C Red No. 40, flavor, polysorbate 20, propylene glycol, saccharin sodium, sodium benzoate, sodium chloride, sodium citrate, sorbitol, sucralose, water, xanthan gum

Member ratings & reviews

4.6 out of 5 stars
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Showing 1-3 of 4 reviews

Mar 5, 2026
Reviewer name: JEANNETTE
5 out of 5 stars
5 out of 5 stars review

Why do you guys do this to us?

Why do you guys have to remove important staples for our home and our personal health bring this back immediately as you can tell I need to sleep don't play with our sleep. Sam's Club. Please bring it back.

Helpful?66C4EG4TT4XY14996253621
Mar 24, 2026
Reviewer name: Herman
5 out of 5 stars
5 out of 5 stars review

Bring this back ASAP :)

This stuff works… and that is saying something when it comes to pain relief. It has saved me from some long nights having difficulty sleeping due to foot, knee, hip and back pain

Helpful?66C4EG4TT4XY14996253621
Jun 23, 2025
Reviewer name: April T
5 out of 5 stars
5 out of 5 stars review

Verified Purchase

Awesome NyQuil medicine works great

Works well so you some rest, great taste.

Helpful?66C4EG4TT4XY14996253621