Excedrin

Excedrin Migraine Pain Relief Caplets, 300 ct.

|6,217 ratings
Item # 990351574
Current price is $18.98
$0.06/ea
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Highlights

  • One bottle of 300 Excedrin Migraine Caplets for Migraine Headache Relief
  • Excedrin Migraine works in 3 ways to relieve migraines: it blocks pain signals, elevates your pain threshold and uses caffeine to enhance the pain relief effect
  • Excedrin migraine caplets for migraine pain relief combine acetaminophen, aspirin and caffeine
  • Pain relievers that provide migraine relief, including migraine headache pain, sensitivity to light and sound, and nausea
  • For some, these Excedrin Migraine caplets relieve migraine pain in 30 minutes
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Excedrin Migraine Pain Relief Caplets, 300 ct.
Excedrin Migraine Pain Relief Caplets, 300 ct.
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About this item

Product details

Caplets for Fast Migraine Relief

Excedrin Migraine Caplets for Migraine Headache Relief provide migraine relief fast, making Excedrin Migraine the number 1 neurologist recommended OTC treatment for migraines (1). Excedrin works in 3 ways to relieve migraines: it blocks pain signals, elevates your pain threshold and uses caffeine to enhance the pain relief effect. Available in convenient caplet form, this powerful migraine medicine delivers a specialized triple action formula containing two pain relievers and an amplifier. These Excedrin caplets combine aspirin and acetaminophen with caffeine to provide migraine relief, including migraine headache pain, sensitivity to light and sound, and nausea. For some, this migraine headache relief medicine starts relieving migraine pain in 30 minutes. Get migraine relief fast with Excedrin, the headache expert.

(1) Among OTC medicine for migraines IQVIA, Inc., 2018

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Specifications

  • Use Instructions: Adults: take 2 caplets with a glass of water. If symptoms persist or worsen, ask your doctor. Do not take more than 2 caplets in 24 hours, unless directed by a doctor. Under 18 years of age: ask a doctor.
  • Purchase Includes: One bottle of 300 caplets
  • Shelf Life: 730 days
  • FSA/HSA Eligible: Yes
  • Allergens + Warnings: Reye's syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness. Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening, blisters, or rash. If a skin reaction occurs, stop use and seek medical help right away. Allergy alert: Aspirin may cause a severe allergic reaction with may include: hives, facial swelling, asthma (wheezing), or shock. Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take more than 2 caplets in 24 hours, which is the maximum daily amount, with other drugs containing acetaminophen, or 3 or more alcoholic drinks every day while using this product. Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you are age 60 or older, have had stomach ulcers or bleeding problems, take a blood thinning (anticoagulant) or steroid drug, take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others), have 3 or more alcoholic drinks every day while using this product, or take more or for a longer time than directed. Caffeine warning: The recommended dose of this product contains about as much caffeine as a cup of coffee. Limit the use of caffeine-containing medications, foods or beverages while taking this product because too much caffeine may cause nervousness, irritability, sleeplessness, and occasionally, rapid heart beat. Do not use if you have ever had an allergic reaction to acetaminophen, aspirin or any other pain reliever/fever reducer. Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. Ask a doctor before use if: you have never had migraines diagnosed by a health professional; you have a headache that is different from your usual migraines; you have the worst headache of your life; you have fever and stiff neck; you have headaches beginning after or caused by head injury, exertion, coughing or bending; you experienced your first headache after the age of 50; you have daily headaches; you have a migraine so severe as to require bed rest; you have liver disease; stomach bleeding warning applies to you; you have a history of stomach problems, such as heartburn; you have high blood pressure, heart disease, liver cirrhosis, kidney disease; you are taking a diuretic; you have asthma; you have problems or serious side effects from taking pain relievers or fever reducers; or you have vomiting with your migraine headache. Ask a doctor or pharmacist before use if you are taking a prescription drug for: diabetes, gout, or arthritis. Ask a doctor or pharmacist before use if you are under a doctor's care for any serious condition, taking any other drug, or taking any other product that contains aspirin, acetaminophen, or any other pain reliever/fever reducer. Stop use and ask a doctor if an allergic reaction occurs. Seek medical help right away. Stop use and ask a doctor if you experience any of the following signs of stomach bleeding: feel faint, vomit blood, have bloody or black stools, or have stomach pain that does not get better. Stop use and ask a doctor if your migraine is not relieved or worsens after first dose, new or unexpected symptoms occur, or ringing in the ears or loss of hearing occurs. If pregnant or breast-feeding, ask a health professional before use. It is especially important not use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
  • Ingredients: Active: (In each caplet): Acetaminophen 250 mg - Pain reliever; Aspirin 250 mg (NSAID†) - Pain reliever; Caffeine 65 mg - Pain reliever aid. † nonsteroidal anti-inflammatory drug. Inactive: benzoic acid, carnauba wax, FD&C blue #1, hydroxypropylcellulose, hypromellose, light mineral oil, microcrystalline cellulose, polysorbate 20, povidone, propylene glycol, simethicone emulsion, sorbitan monolaurate, stearic acid, titanium dioxide

Indications

Health Concern

Headache

Member ratings & reviews

4.8 out of 5 stars
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6,217 ratings5,155 reviews
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  1. 5 stars84% (5,223)
  2. 4 stars11% (699)
  3. 3 stars3% (186)
  4. 2 stars1% (42)
  5. 1 star1% (67)
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Showing 1-3 of 5,155 reviews

Sep 16, 2026
Reviewer name: Donna
5 out of 5 stars
5 out of 5 stars review

Verified Purchase

This is my go to when I feel a migraine coming on, which for me, are typically brought on by changes in the weather. These are the only OTC meds that I have found that work for me.

Review from walmart.com
Helpful?1LKVI83KUKAH30067203933
Oct 26, 2025
Reviewer name: No shirt
5 out of 5 stars
5 out of 5 stars review

Verified Purchase

Best OTC Migraine Medication

This is basically the only medication that will remove my migraines. I take prescription medication and it doesn’t even touch my headache. I know this contains many MG of acetaminophen but for me, this works.

Helpful?1LKVI83KUKAH30067203933
Sep 3, 2026
Reviewer name: Kricket
5 out of 5 stars
5 out of 5 stars review

Verified Purchase

Headache RELIEF!!

These Excedrin work very well for the headaches I get in the evening and morning. I usually take two and within twenty minutes I get relief from the pain. I highly recommend these migraine relief Excedrin.

Review from walmart.com
Helpful?1LKVI83KUKAH30067203933