Similac
In 900+ people's carts

Similac 360 Total Care Gentle Comfort Infant Formula, 40 oz.

|8 ratings
Item # 990470884
Current price is $53.98
$1.35/oz
Prices may vary in club and online
Similac 360 Total Care Gentle Comfort Infant Formula, 40 oz.Similac 360 Total Care Gentle Comfort Infant Formula 40 ozSimilac 360 Total Care Gentle Comfort Infant Formula 40 oz
Size40 oz. Tub
How do you want your item?

Shipping

Free for Plus on eligible orders over $50
Columbus, 43215
Return or replace anytime.
SNAP EBT eligible, pickup or delivery only
Sam's credit card
Get a $30 statement credit¹ when you open an account 9/1-9/30/26 + learn how to earn 10% back on fuel for a limited time‡ See details

Highlights

  • 40 oz. tub of powdered infant formula     
  • 360 whole baby support for infants up to 12 months   
  • Gentle, easy-to-digest protein for delicate tummies   
  • No artificial growth hormones† and non-GMO‡   
  • Similac is the #1 Infant Formula brand fed in hospitals
We also recommend

Nurri Kids 10g Protein Ultra-Filtered Milk Shake, Chocolate, 8 fl. oz. 12 pk. $13.98 Was $17.98 $0.15/foz

Nurri Kids 10g Protein Ultra-Filtered Milk Shake, Chocolate, 8 fl. oz. 12 pk.
current price Now $13.98, Was $17.98
$0.15/foz

Nurri Kids 10g Protein Ultra-Filtered Milk Shake, Chocolate, 8 fl. oz. 12 pk.

4.0825 out of 5 stars
4.0825 out of 5 Stars. 97 reviews
Sponsored
similac 360 total care gentle comfort infant formula, 40 oz. front-facing powdered formula tub with purple lid and label reading 'Similac 360 Total Care', '5 HMO prebiotics' badge and label text noting immune support, brain development and digestive health, net wt. 40 oz (1.13 kg); often used to store single-use formula packets for travel.
Similac 360 Total Care Gentle Comfort Infant Formula, 40 oz.
Hero image 0 of Similac 360 Total Care Gentle Comfort Infant Formula, 40 oz., 0 of 9

About this item

Product details

Easy-to-Digest Formula for Fussiness and Gas

Similac 360 Total Care Gentle Comfort is specially designed for babies experiencing fussiness and gas due to lactose sensitivity. This formula features partially hydrolyzed whey protein, making it easier to digest for delicate tummies that struggle with other milk-based formulas.

Closest Prebiotic Blend to Breast Milk

Similac 360 Total Care Gentle Comfort includes an exclusive blend of 5 HMO prebiotics, structurally identical to those found in breast milk. These prebiotics are designed to support your baby's digestive health and overall well-being.

360 Gentle Whole-Baby Support

This formula provides comprehensive nutrition to support your baby's immune system, brain development, and digestive health. It contains easy-to-digest protein and is free from palm olein oil, promoting softer stools for your little one.

First and Only Gentle Formula with 5 HMOs

Similac 360 Total Care Gentle Comfort is the first and only gentle infant formula to feature 5 HMO prebiotics. This unique formulation also includes DHA and lutein, essential components found in breast milk that support brain and eye development.

No Artificial Growth Hormones and Non-GMO Ingredients

Similac 360 Total Care Gentle Comfort is made without artificial growth hormones and contains non-GMO ingredients, ensuring high-quality nutrition for your baby.

info:
If the item details above aren't accurate or complete, we want to know about it. 

Specifications

Key Specifications
Product Type/Size/Count: One 40 oz. tub of powder infant formula; Makes approximately 73 four fl. oz. bottles
Form: Powder
Stage & Age Range: For infants up to 12 months of age
Ingredient List: Corn maltodextrin, whey protein hydrolysate, high oleic safflower oil, sugar, soy oil, coconut oil, human milk oligosaccharides (2′-fucosyllactose, lacto-N-tetraose, 3-fucosyllactose, 6′-sialyllactose, 3′-sialyllactose); less than 2% of: Schizochytrium sp. oil, M. alpina oil, Beta-carotene, lutein, calcium citrate, potassium phosphate, calcium phosphate, salt, magnesium chloride, ascorbic acid, choline chloride, inositol, potassium chloride, sodium citrate, calcium hydroxide, potassium citrate, choline bitartrate, ferrous sulfate, taurine, zinc sulfate, ascorbyl palmitate, L-carnitine, niacinamide, mixed tocopherols, d‑alpha‑tocopheryl acetate, calcium pantothenate, copper sulfate, vitamin A palmitate, thiamine hydrochloride, riboflavin, pyridoxine hydrochloride, folic acid, manganese sulfate, potassium iodide, phylloquinone, biotin, sodium selenate, vitamin D₃, vitamin B₁₂, potassium hydroxide, and nucleotides (adenosine 5′‑monophosphate, cytidine 5′‑monophosphate, disodium guanosine 5′‑monophosphate, disodium uridine 5′‑monophosphate). Contains Milk Ingredients.
Use Instructions: 1. Wash your hands, surfaces, and utensils pour water into clean bottle (See mixing guide). 2. Add 1 unpacked level scoop (8.8g) to each 2 fl oz water, return dry scoop to holder in lid. 3. Cap bottle; shake well; attach nipple. Once feeding begins, use within 1 hour or discard.
Safe Handling Instructions: Once mixed, feed to baby within 1 hour or discard.
Container Type: Simplepac plastic container

Member ratings & reviews

4.4 out of 5 stars
stars
8 ratings5 reviews
Write a review
  1. 5 stars75% (6)
  2. 4 stars13% (1)
  3. 3 stars0% (0)
  4. 2 stars0% (0)
  5. 1 star13% (1)
Filtered and sorted results would be available on the new 'Customer ratings & reviews' page.
Sort by |

Showing 1-3 of 5 reviews

May 10, 2026
Reviewer name: anonymous
5 out of 5 stars
5 out of 5 stars review

Happy Baby 💙

Ordered late night May 2nd, got here May 4th. Better than other retailers on shipping. No damage. The can is plastic, has a holder for the scoop and is the best price/value on the market, period. This is better than Enfamil's Gentlease as it doesn't have palm oil and has more HMOs. My baby did not like Gentlease. I combo feed with breastmilk, no issues with mixing. No spit up, drinks like a champion. Some gas but much less than the orange can (Sensitive) and burping time has been cut in half. I have a happy baby boy!

Helpful?1P3EOVER0E2619148959439
reply from Abbott Nutrition Team

We would like to learn more about your baby's experience and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04990566 when you call. - The Similac Team

Jul 27, 2026
Reviewer name: Mary
5 out of 5 stars
5 out of 5 stars review

the best

this is the best formula for baby. it's more expensive than the other ones but 100% worth it. my baby doesn't get any trapped gas or constipation and digests this very well.

Helpful?1P3EOVER0E2619148959439
Jul 8, 2026
Reviewer name: Bob272727
5 out of 5 stars
5 out of 5 stars review

Great taste and mix great with water

[This review was collected as part of a promotion.] Bought this couple of weeks and very happy with it. My kid likes it and seeing good results so far.

Review from similac.com
Helpful?1P3EOVER0E2619148959439

Related pages