excedrin extra strength pain reliever caplets, 300 ct. Front-facing white plastic bottle with green screw cap and dark-green label reading Excedrin Extra Strength; label lists active ingredients acetaminophen, aspirin (NSAID) and caffeine, includes a white caplet graphic and '300 caplets' callout on a plain white background; label indicates relief for headaches, migraines and other types of pain.
Excedrin Extra Strength Pain Reliever Caplets, 300 ct.
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Excedrin

Excedrin Extra Strength Pain Reliever Caplets, 300 ct.

|6,376 ratings

Highlights

  • Relief for headaches, migraines, and other types of pain
  • Combination pain reliever with 2 pain fighters and 1 booster
  • For some, relief starts as soon as 15 minutes
  • Excedrin, a leader in headache relief for more than 50 years

Specifications

  • 300 ct.
  • Acetaminophen 250 mg. - pain reliever
  • Aspirin 250 mg. - pain reliever
  • Caffeine 65 mg. - pain reliever aid
  • Ages 12 and older take 2 caplets every 6 hours
  • Drink a full glass of water with each dose
  • Ages 12 and under ask doctor before use
  • Use as directed

While we strive to obtain accurate product information, we cannot guarantee or ensure the accuracy, completeness or timeliness of any product information. Carefully read and follow all package directions. SamsClub.com assumes no liability for inaccuracies or misstatements about products.

Current price is $18.986.3 ¢/ea
Prices may vary in club and online
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Shipping

Free for Plus on eligible orders over $50
Columbus, 43215
Arrives by Mon, Nov 2
.
Order within 9 hr 1 min
Return or replace anytime.
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About this item

Product details

For quick relief, reach for Excedrin Extra Strength Caplets. If you're dealing with headaches, migraines, or any other type of pain, many doctors recommend Excedrin Extra Strength before taking any prescription pain relievers.

Why Excedrin?

Excedrin Extra Strength Caplets provide the necessary relief you need whenever pain, migraines, and headaches strike. For many, relief starts just 15 minutes after you take your dose. For the past 50 years, Excedrin has been a trusted leader in headache and migraine relief. With Excedrin Extra Strength Caplets, you receive quick pain relief you can trust.

Relief for Minor Aches and Pains

Don't let aches and pains slow you down! Our formula provides trusted and quick relief for minor aches and pains that can be caused by tootaches, premenstrual and menstrual cramps, muscle aches, arthritis, headaces, and the cold. 

Ingredients

The three primary ingredients in Excedrin are 250 mg. of acetaminophen extra strength, 250 mg. of aspirin, and 65 mg. of caffeine. Both acetaminophen and aspirin fight pain for your relief, while the caffeine works to re-energize you. Also, research supports caffeine as a key contributor to headache and migraine relief. The combination of caffeine, acetaminophen, and aspirin increases the pain relieving effect by as much as 40%. 

info:
If the item details above aren't accurate or complete, we want to know about it. 

Key specifications

Specifications

  • 300 ct.
  • Acetaminophen 250 mg. - pain reliever
  • Aspirin 250 mg. - pain reliever
  • Caffeine 65 mg. - pain reliever aid
  • Ages 12 and older take 2 caplets every 6 hours
  • Drink a full glass of water with each dose
  • Ages 12 and under ask doctor before use
  • Use as directed

While we strive to obtain accurate product information, we cannot guarantee or ensure the accuracy, completeness or timeliness of any product information. Carefully read and follow all package directions. SamsClub.com assumes no liability for inaccuracies or misstatements about products.

Indications

Health Concern

Headache

Member ratings & reviews

4.7 out of 5 stars
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6,376 ratings5,878 reviews
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  1. 5 stars82% (5,234)
  2. 4 stars13% (851)
  3. 3 stars3% (175)
  4. 2 stars1% (53)
  5. 1 star1% (63)
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Showing 1-3 of 5,878 reviews

Sep 21, 2026
Reviewer name: AshleyA
5 out of 5 stars
5 out of 5 stars review

Products works

[This review was collected as part of a promotion.] Excedrin Extra Strength is my go to for those stubborn body aches & pains that just won't go away. Great product and works within 10-15 minutes. Texture is great providing a nice coating to easily swallow the pills. I would recommend this product for aches, pains and body aches.

Review from Excederin
Helpful?4GYNGM7F2P9K30067810433
Sep 11, 2026
Reviewer name: LisbetC
5 out of 5 stars
5 out of 5 stars review

Relieves headache quickly, cleanly and with a very long-lasting effect.

[This review was collected as part of a promotion.] Since I tried this product I was surprised, the consistency of its results is excellent. The dosage of two tablets is perfect to stop the headache quickly. It leaves no feeling of stomach heaviness or traces of bitter taste. In addition, the duration of its effect is prolonged, which allows me to continue with my day without relapses.

Review from Excederin
Helpful?4GYNGM7F2P9K30067810433
Oct 13, 2026
Reviewer name: Renee
5 out of 5 stars
5 out of 5 stars review

Verified Purchase

Excellent works terrific for headaches and all body pain. The only other one I get is Excedrin tension is when I have headache in my neck and above, but Excedrin works for me terrifically both of them would recommend them 1000%.

Review from walmart.com
Helpful?4GYNGM7F2P9K30067810433
Current price is $18.986.3 ¢/ea
Prices may vary in club and online
How do you want your item?

Shipping

Free for Plus on eligible orders over $50
Columbus, 43215
Arrives by Mon, Nov 2
.
Order within 9 hr 1 min
Return or replace anytime.

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